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Reading: Unique: Callosum, a startup trying to break Nvidia’s stranglehold on AI workloads, raises $10.25 million in new funding | Fortune
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Asolica > Blog > Business > Unique: Callosum, a startup trying to break Nvidia’s stranglehold on AI workloads, raises $10.25 million in new funding | Fortune
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Unique: Callosum, a startup trying to break Nvidia’s stranglehold on AI workloads, raises $10.25 million in new funding | Fortune

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Last updated: February 26, 2026 7:24 am
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9 hours ago
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Unique: Callosum, a startup trying to break Nvidia’s stranglehold on AI workloads, raises .25 million in new funding | Fortune
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A London-based startup based by two Cambridge-trained neuroscientists has raised $10.25 million for his or her startup Callosum, which is constructing software program that orchestrates AI workloads throughout a mixture of totally different chip varieties—difficult the trade’s dependence on working ever-bigger fashions on banks of similar Nvidia GPUs.

The corporate additionally introduced it’s receiving analysis funding from the U.Okay. authorities which is searching for methods to construct so-called “sovereign cloud” infrastructure for AI that might be unbiased, or at the least not solely reliant, on U.S. know-how suppliers.

Callosum cofounders Danyal Akarca and Jascha Achterberg, who met throughout their PhDs at Cambridge round 2019, have software program that may distribute AI duties throughout chips from totally different producers—be it Nvidia GPUs, AMD processors, Amazon Internet Companies’ customized Trainium and Inferentia silicon, or newer designs from startups like Cerebras and SambaNova—extracting efficiency benefits from every.

The funding spherical was led by Plural, the European early-stage enterprise fund co-founded by Clever’s Taavet Hinrikus and Ian Hogarth, who additionally served as the primary chair of the U.Okay.’s AI Security Institute. Angel traders together with Charlie Songhurst, Stan Boland of FiveAI, and John Lazar of the Royal Academy of Engineering additionally participated. Individually, the U.Okay. authorities’s Superior Analysis and Invention Company (ARIA) is offering grant funding to the corporate to speed up R&D on integrating novel chip applied sciences into its platform—although ARIA shouldn’t be an investor within the spherical itself, Akarca stated in an interview with Fortune.

The corporate’s thesis is rooted within the cofounders’ educational analysis on the intersection of neuroscience and computing: the human mind doesn’t obtain intelligence by copying one kind of neuron billions of instances, however by combining many various specialised cell varieties and circuits that work collectively. They consider AI computing ought to comply with the identical precept.

“Big labs are currently betting that one model will rule them all. We think that’s wrong and our work proves this,” Akarca stated. “Nature shows that real intelligence emerges from many systems working together.”

Callosum enters a market present process a profound structural shift. After years wherein AI spending was dominated by coaching huge basis fashions on racks of similar Nvidia GPUs, the trade is now pivoting towards inference—the method of truly working skilled fashions to provide outputs. Deloitte has estimated that inference workloads will account for roughly two-thirds of all AI compute in 2026, up from a 3rd in 2023, and that the marketplace for inference-optimized chips will develop to greater than $50 billion this 12 months. That shift is creating openings for a various array of chipmakers to problem Nvidia’s dominance.

Callosum is betting it may be the software program layer that ties this more and more fragmented {hardware} panorama collectively. Its platform works throughout a number of cloud suppliers, together with AWS, Google Cloud, and Microsoft Azure, and is designed in order that clients don’t need to re-architect their current cloud setups to make use of it. “It’s a software product which takes your AI workload and orchestrates it across the different multi-cloud setup that you might use,” Akarca stated.

The cofounders argue the strategy yields massive positive factors on advanced, real-world duties that contain many various kinds of selections—reminiscent of automating laptop use or processing enterprise workflows. For duties like these, Callosum says its system can ship twice the accuracy, seven instances sooner efficiency, and 4 instances decrease value in comparison with working the identical workloads on similar {hardware}.

Achterberg defined that the accuracy positive factors come from the character of the issues being solved. “Simple problems, single models are perfectly fine,” he stated. However advanced enterprise duties are a distinct matter. “Automating how computers are used, automating payments, for example—these are problems that we focus on. They are inherently heterogeneous,” Achterberg stated. “There’s actually many, many, many steps involved in solving the problem, and a single model actually isn’t always optimal.”

Completely different elements of a fancy workflow could require various things—some steps want very quick, low cost fashions that may iterate quickly by means of trial and error, whereas others require bigger, extra succesful reasoning. By matching every subtask to the fitting mannequin working on the fitting {hardware}, Callosum says it could possibly outperform the standard strategy of throwing one highly effective mannequin on the whole drawback.

Callosum is concentrating on two forms of clients: firms constructing multi-agent AI programs that want superior efficiency throughout advanced workflows, and rising chip producers that wish to reveal their {hardware}’s capabilities at scale. “What we want is that all these new chip technologies, which are amazing, have amazing performance, amazing benefits, find a way into the market where we can actually realize them,” Achterberg stated.

The corporate can also be working with firms engaged on new methods to attach racks of AI chips inside knowledge facilities—which is known as “interconnect”—together with these growing networking based mostly on photonics, know-how that transmits knowledge utilizing gentle as an alternative {of electrical} pulses. These applied sciences are designed to handle bottlenecks that come from having to shuffle knowledge round inside an information middle—a problem that grows extra advanced as totally different chip varieties want to speak with each other.

Trying forward, the cofounders say they plan to make use of the funding to develop their London-based workforce, start scaling into the U.S., and begin constructing out their very own complementary {hardware} infrastructure. Their longer-term ambition extends past software program to basically rethinking knowledge middle design itself.

“Everyone assumed chip diversity was a disadvantage to be managed. We saw the opposite, that it’s an advantage to be exploited,” Achterberg stated. “We’re not optimizing one algorithm on top of the existing stack. We’re using software to control all the levers across the entire system, extracting benefits from diversity that others dismiss.”

Ian Hogarth, associate at Plural, stated in an announcement: “[Callosum’s] vision for a multi-model, multi-chip future could be transformative and positions them to compete with the world’s biggest chip and model makers. These are serious founders tackling a serious mission.”

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