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Asolica > Blog > Marketing > Are these 2 of probably the most worthwhile UK shares on the FTSE 100? My cash says ‘sure’
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Are these 2 of probably the most worthwhile UK shares on the FTSE 100? My cash says ‘sure’

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Last updated: December 3, 2025 8:36 am
Admin
5 days ago
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Are these 2 of probably the most worthwhile UK shares on the FTSE 100? My cash says ‘sure’
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Contents
  • AstraZeneca 
  • HSBC

Picture supply: Getty Pictures

When trying to find UK shares to purchase, profitability needs to be one of many first areas of analysis. Whether or not searching for development alternatives or dividend shares, profitability is a essential measure of a inventory’s long-term potential.

To measure profitability, traders usually take a look at a couple of key return-focused metrics. The most typical are return on fairness (ROE), return on capital employed (ROCE) and return on belongings (ROA). These measures are only when evaluating shares in the identical trade, as this has a notable impact on their relevance.

Along with measuring return-based metrics, it’s vital to take a look at margins. These consider how nicely a enterprise is changing income into earnings. Widespread ones embrace the gross margin, working margin and internet margin. Every stage reveals the place revenues are being depleted, with internet margin being the underside line.

Lastly, the EBITDA margin’s an excellent measure of how nicely a enterprise converts income to money, with out the obscurity of unavoidable bills.

To indicate how this works in follow, I’ve utilized the evaluation to 2 of the perfect recognized UK shares on the FTSE 100.

AstraZeneca 

AstraZeneca (LSE: AZN) stands out as exceptionally worthwhile when evaluated utilizing the metrics mentioned above. The pharmaceutical firm demonstrates a internet revenue margin of 16.2%, considerably greater than most FTSE friends and nicely above the sector median.

Extra impressively, its return on fairness (ROE) is round 22%, inserting it among the many highest within the index. This distinctive ROE displays the corporate’s effectivity at changing every pound of shareholder fairness into substantial revenue.

The corporate additionally maintains a powerful working margin of 21.8%, indicating sturdy pricing energy and price management in its core pharmaceutical enterprise. For traders searching for sustainable development, it seems to be an inexpensive inventory to contemplate.

Nonetheless, it isn’t with out danger. The upcoming pharmaceutical patent cliff on its key drug Farxiga may drastically alter future earnings. The patent expires subsequent yr, placing in danger a possible $7.7bn in income. A number of different medication additionally face expiration earlier than 2030, together with Lynparza, so the corporate should proceed to innovate to stay related.

HSBC

When wanting on the finance sector, we have to apply barely completely different metrics. With regards to banking, HSBC‘s (LSE: HSBA) extremely worthwhile when measured by return on tangible fairness (RoTE).

The financial institution achieved an annualised RoTE of 17.6% year-to-date in 2025, with some quarters reaching 16.4%. Whereas its conventional ROE stands at round 13%, which is respectable for banking, the RoTE metric is extra related for monetary establishments. It’s because it excludes goodwill and intangible belongings that distort profitability evaluation.

The financial institution’s robust profitability stems from numerous income streams, notably wealth administration, the place it demonstrated important development and excessive margins.​ However whereas it’s definitely a compelling inventory to consider within the UK banking sector, it isn’t risk-free.

Earlier this yr, HSBC disbanded its devoted geopolitical danger crew, absorbing this operate into generalist departments as a cost-cutting measure. This determination has drawn scrutiny, as analysis from the Financial institution for Worldwide Settlements (BIS) warns that banks underestimating geopolitical dangers face 30% greater earnings volatility throughout crises.

With rivals like JPMorgan Chase utilizing AI to increase its geopolitical consciousness, HSBC’s vulnerable to falling behind.

Nonetheless, with spectacular metrics backed by a long time of outstanding efficiency, it stays one of the worthwhile UK shares on the FTSE 100.

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Skipping this after the Autumn Funds may price you dearly…
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