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Reading: After his son was paralyzed, an NFL Corridor of Famer resolved to discover a treatment. 40 years and $550 million later, his basis is credited with enhancing tens of millions of lives: | Fortune
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Asolica > Blog > Business > After his son was paralyzed, an NFL Corridor of Famer resolved to discover a treatment. 40 years and $550 million later, his basis is credited with enhancing tens of millions of lives: | Fortune
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After his son was paralyzed, an NFL Corridor of Famer resolved to discover a treatment. 40 years and $550 million later, his basis is credited with enhancing tens of millions of lives: | Fortune

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Last updated: November 28, 2025 1:33 pm
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1 week ago
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After his son was paralyzed, an NFL Corridor of Famer resolved to discover a treatment. 40 years and 0 million later, his basis is credited with enhancing tens of millions of lives: | Fortune
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Contents
  • Altering medication by making a hub for paralysis work
  • Surprising advances by multidisciplinary approaches
  • ‘They hooked me’

Marc Buoniconti mentioned his father, the late NFL Corridor of Famer Nick Buoniconti, defined the key to the success of their nonprofit and its fundraising efforts merely: “We’re just not good listeners.”

Within the 40 years since Marc Buoniconti, then a university soccer linebacker on the Citadel, was paralyzed throughout a routine deal with, they’ve been instructed numerous instances that it was an issue that couldn’t be fastened. The Buonicontis didn’t hear.

As an alternative, by the fund that bears their title, they’ve helped increase greater than $550 million for The Miami Mission to Treatment Paralysis, and improved the lives of tens of millions with spinal twine and mind accidents.

“The Buoniconti Fund has lasted because we’re relentless,” Marc Buoniconti lately instructed The Related Press. “We never give up. When we see a challenge, we face it head-on and don’t stop until we find a solution. It’s that determination, that refusal to quit that’s kept us going all these years.”

That drive has additionally led The Miami Mission to increase its work past curing paralysis. Its analysis heart on the College of Miami Miller College of Drugs now additionally research neurological illnesses and problems together with Alzheimer’s illness and Parkinson’s illness, and it’s testing the brain-computer interface implant from Elon Musk’s know-how firm Neuralink.

Altering medication by making a hub for paralysis work

Dr. Barth A. Inexperienced, chairman of The Miami Mission, who co-founded the group in 1985 with Nick Buoniconti, says essentially the most stunning developments from the middle have been the broadest ones.

“Every operating room in the world that puts people to sleep monitors their nervous system for safety,” Dr. Inexperienced mentioned. “That was all developed at The Miami Project.”

Therapeutic hypothermia, the place the physique is cooled after an damage to guard the mind and spinal twine, is one other extensively used remedy developed on the heart.

Dr. Inexperienced mentioned that earlier than Buoniconti’s accident he had been engaged on serving to those that had been paralyzed for 20 years. But there wasn’t a hub for that work till The Miami Mission was established.

It offered a house for him and “thousands of scientists and researchers in Miami and around the world, who were equally engaged by the opportunity to change people’s everyday quality of life and their opportunities to have more function and a better opportunity to be mobile and do things they never dreamt they could before.”

Surprising advances by multidisciplinary approaches

Miami Mission Scientific Director W. Dalton Dietrich III mentioned gathering these folks from a wide range of disciplines – neuroscientists, researchers, clinicians, biomedical engineers – into one constructing has led to sudden advances.

“Not one particular treatment is going to cure paralysis,” Dietrich mentioned. “So I’ve tried to look at other disciplines to bring into the project to help us achieve that goal.”

One new, multidisciplinary space, neuromodulation, is “something we never thought about five years ago,” Dietrich mentioned. “It’s just an exciting area where you can stimulate these residual circuits after brain injury or spinal cord injury in patients and they start moving their limbs.”

The Buoniconti Fund’s help for the middle helps speed up analysis in these areas by funding early trials. That, in flip, makes it simpler to finally obtain grants from authorities companies just like the Nationwide Institutes of Well being or the Division of Protection, Dietrich mentioned.

Marc Buoniconti says “it’s hard to put into words” seeing so many individuals rally behind him and the tens of millions of others who’ve been paralyzed.

“What started as a promise to help me walk again became a mission to help millions,” he mentioned. “Every resource, every dollar, every hour given is a testament to the belief that we can change lives.”

Mark Dalton, co-chairman of Tudor Funding Corp., mentioned that perception resonated with him and made him wish to get entangled with The Buonicontis even earlier than he met them.

“I had tremendous admiration for him as a father who was never going to give up on finding a cure for what ailed his son,” Dalton mentioned. “And his son was a representation of millions of other people.”

‘They hooked me’

As soon as he realized extra about The Miami Mission, Dalton mentioned he was impressed by its science-driven method. Its setting on a college campus was additionally essential to the previous chairman of the board of trustees at Denison and Vanderbilt universities.

“They put the line in the water,” mentioned Dalton, who now chairs the Buoniconti Fund’s greatest annual fundraiser, The Nice Sports activities Legends Dinner. “They hooked me. I’m all in.”

That’s a standard feeling round The Miami Mission, which counts legendary golfer Jack Nicklaus and Grammy winner Gloria Estefan amongst its supporters. And it’s one thing Marc Buoniconti says he doesn’t take as a right.

He hopes The Miami Mission’s work will proceed to increase.

“My biggest dream is for our researchers to find a way to fully repair the nervous system,” Buoniconti mentioned. “When we do that, we’ll change the entire landscape for paralysis and so many other neuro conditions. We’ll give so many people their lives back. That’s what keeps me going, and that’s what makes every struggle to this point worth it.”

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